Myocarditis: An Interleukin-1-Mediated Disease?
نویسندگان
چکیده
منابع مشابه
Serum troponin I as an indicator of myocarditis in lambs affected with foot and mouth disease
Foot and mouth disease (FMD) is a highly contagious viral disease of cloven-hooved livestock and wildlife results to relatively high mortality in young animals. Despite the numerous reports of FMD-related death in neonates, there is little data available on various aspects of FMD in lambs. This report describes myocarditis associated with FMD in five, one week to three months old lambs. The lam...
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One of the most serious neurodegenerative disorders is Alzheimer disease (AD). As the population is aging and due to the fact that AD is more common in aged people, more attention must be paid to this disease. One of the main characteristics of AD is dementia which starts with loss of short term memory, then progresses and causes various brain dysfunctions such as loss of long term memory. Inte...
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To understand the role of the proinflammatory cytokine interleukin-1 (IL-1) in disease, investigators have studied how production of the different members of the IL-1 family is controlled, the various biologic activities of IL-1, the distinct and various functions of the IL-1 receptor (IL-1R) family, and the complexity of intracellular signaling. Mice deficient in IL-1Beta, IL-1Beta converting ...
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BACKGROUND The pathologic diagnosis of isolated myocarditis without pericardial involvement is uncommonly encountered in systemic onset Juvenile Idiopathic Arthritis (soJIA). CASE An eleven year-old boy with soJIA died suddenly while being treated with the interleukin 1 (IL-1) receptor inhibitor, anakinra. His autopsy revealed an enlarged heart and microscopic findings were consistent with my...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2018
ISSN: 1664-3224
DOI: 10.3389/fimmu.2018.01335